Article
Increased expression of alpha 1-anti-trypsin in the synovial tissues of patients with ankylosing spondylitis.
Clinical and experimental rheumatology - 1 Jan 2000
Sun S, Fang K, Zhao Y, Yan X, Chang X
Abstract excerpt
OBJECTIVES: Evidence indicates that the hyperplasia and inflammation of synovial tissues are significantly related to the pathogenic process of ankylosing spondylitis (AS). Using a proteomics approach, we detected a significantly increased expression of alpha 1-anti-trypsin (ATA1) in synovial membranes of patients with AS. METHODS: We continued to investigate the expression level and location of ATA1 in synovial...
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