Article
Genetic variants of FOXP2 and KIAA0319/TTRAP/THEM2 locus are associated with altered brain activation in distinct language-related regions.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 18 Jan 2012
Pinel Philippe, Fauchereau Fabien, Moreno Antonio, Barbot Alexis, Lathrop Mark, Zelenika Diana, Le Bihan Denis, Poline Jean-Baptiste, Bourgeron Thomas, Dehaene Stanislas
Abstract excerpt
Recent advances have been made in the genetics of two human communication skills: speaking and reading. Mutations of the FOXP2 gene cause a severe form of language impairment and orofacial dyspraxia, while single-nucleotide polymorphisms (SNPs) located within a KIAA0319/TTRAP/THEM2 gene cluster and affecting the KIAA0319 gene expression are associated with reading disability. Neuroimaging studies of clinical...
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