Article
Behavioral effects of prenatal ketamine exposure in rhesus macaques are dependent on MAOA genotype.
Experimental and clinical psychopharmacology - 1 Jun 2012
Capitanio John P, Del Rosso Laura A, Calonder Laura A, Blozis Shelley A, Penedo M Cecilia T
Abstract excerpt
Ketamine is an N-methyl-D-aspartate (NMDA) receptor antagonist that is used in anesthetic, abuse, and therapeutic contexts. Recent evidence suggests that ketamine may affect not only glutamate systems, but may also act on receptors in the dopamine and serotonin systems. Because monoamine neurotransmitters play important trophic roles in prenatal development, we hypothesized that the behavioral consequences of...
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