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Article

Meckelin is necessary for photoreceptor intraciliary transport and outer segment morphogenesis.

Investigative ophthalmology & visual science - 1 Feb 2012

Collin Gayle B, Won Jungyeon, Hicks Wanda L, Cook Susan A, Nishina Patsy M, Naggert Jürgen K

Abstract excerpt

PURPOSE: Cilia, complex structures found ubiquitously in most vertebrate cells, serve a variety of functions ranging from cell and fluid movement, cell signaling, tissue homeostasis, to sensory perception. Meckelin is a component of ciliary and cell membranes and is encoded by Tmem67 (Mks3). In this study, the retinal morphology and ciliary function in a mouse model for Meckel Syndrome Type 3 (MKS3) throughout...

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Identifiers

PMID: 22247471
DOI: 10.1167/iovs.11-8766
PMCID: PMC3317434

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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