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Article

A novel restriction-modification system is responsible for temperature-dependent phage resistance in Listeria monocytogenes ECII.

Applied and environmental microbiology - 1 Mar 2012

Kim Jae-Won, Dutta Vikrant, Elhanafi Driss, Lee Sangmi, Osborne Jason A, Kathariou Sophia

Abstract excerpt

Listeria monocytogenes epidemic clone II (ECII) strains are unusual in being completely resistant to phage when grown at low temperatures (≤30°C). In the current study we constructed and characterized a mariner-based mutant (J46C) of the ECII strain H7550-Cd(S) that lacked temperature-dependent resistance to phage. The transposon was localized in LMOh7858_2753 (open reading frame [ORF] 2753), a member of a 12-ORF...

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Share to Bacteriophages
Share to DNA Restriction-Modification Enzymes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22247158
DOI: 10.1128/AEM.07086-11
PMCID: PMC3298167

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