Article
Study of genetic stability of human bone marrow multipotent mesenchymal stromal cells.
Bulletin of experimental biology and medicine - 1 Mar 2011
Nikitina V A, Osipova E Yu, Katosova L D, Rumyantsev S A, Skorobogatova E V, Shamanskaya T V, Bochkov N P
Abstract excerpt
Immunophenotype, proliferation rate, and genetic stability parameters of bone marrow multipotent mesenchymal stromal cells were studied. Despite the reduction of proliferative activity by passages 11-12, the cells retained the characteristic immunophenotype. The incidence of spontaneous aneuploidy for autosomes 6, 8, 11 and sex chromosomes was evaluated. Two cultures of mesenchymal stromal cells carrying...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
