Article
The challenges of studying complex and dynamic regions of the human genome.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012
Hollox Edward J
Abstract excerpt
Recent work has emphasised that the human genome is not simple and static, but complex and dynamic. This review focuses on the regions that are particularly hard to dissect and analyse, yet hold clues to how the genome changes during evolution and disease. I begin by summarising recent key advances in the understanding of the variable structure of our genome, and then I discuss a medley of methods that may allow...
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