Article
[Structural variation in the human genome].
Yi chuan = Hereditas - 1 Aug 2009
He Yong-Shu, Zhang Wen, Yang Zhao-Qing
Abstract excerpt
Genomic structural variation is generally defined as deletions, insertions, duplications, inversions, translocations or copy number variation (CNV) in large DNA segments (>1 kb). The structural variation in an individual genome includes thousands of discrete regions, spans millions of base pairs, and encompasses numerous entire genes and their regulatory regions. This results in missing or change of gene...
Topics
- Disease
- Genetic Techniques
- Genetic Variation
- Genome, Human
- Humans
- Mutation