Article
Using ESTs database to predict and validate single polymorphisms at the HLA system.
International journal of immunogenetics - 1 Jun 2012
Figueiredo T C, de Oliveira J R M
Abstract excerpt
We propose a bioinformatics pipeline in which we use an ESTs database to predict and validate single-nucleotide polymorphisms (SNPs) directly linked to gene-coding regions at the HLA class I genes (HLA-A, HLA-B and HLA-C). Annotation originated from our analysis revealed various classes of possible new variations that may indicate possible new alleles. Thus, bioinformatics pipelines seem to be useful approaches...
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