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Article

Prioritisation of candidate Single Amino Acid Polymorphisms using one-class learning machines.

International journal of computational biology and drug design - 1 Jan 2011

Wu Jiaxin, Gan Mingxin, Jiang Rui

Abstract excerpt

Recent advancements of the next-generation sequencing technology have enabled the direct sequencing of rare genetic variants in both case and control individuals. Although there have been a few statistical methods for uncovering potential associations between multiple rare variants and human inherited diseases, most of these methods require computational approaches to filter out non-functional variants for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22199033
DOI: 10.1504/IJCBDD.2011.044446

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