Article
Fine tuning genomic evaluations in dairy cattle through SNP pre-selection with the Elastic-Net algorithm.
Genetics research - 1 Dec 2011
Croiseau Pascal, Legarra Andrés, Guillaume François, Fritz Sébastien, Baur Aurélia, Colombani Carine, Robert-Granié Christèle, Boichard Didier, Ducrocq Vincent
Abstract excerpt
For genomic selection methods, the statistical challenge is to estimate the effect of each of the available single-nucleotide polymorphism (SNP). In a context where the number of SNPs (p) is much higher than the number of bulls (n), this task may lead to a poor estimation of these SNP effects if, as for genomic BLUP (gBLUP), all SNPs have a non-null effect. An alternative is to use approaches that have been...
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