Article
Phosphoproteome exploration reveals a reformatting of cellular processes in response to low sterol biosynthetic capacity in Arabidopsis.
Journal of proteome research - 3 Feb 2012
Heintz Dimitri, Gallien Sebastien, Compagnon Vincent, Berna Anne, Suzuki Masashi, Yoshida Shigeo, Muranaka Toshiya, Van Dorsselaer Alain, Schaeffer Christine, Bach Thomas J, Schaller Hubert
Abstract excerpt
Sterols are membrane-bound isoprenoid lipids that are required for cell viability and growth. In plants, it is generally assumed that 3-hydroxy-3-methylglutaryl-CoA-reductase (HMGR) is a key element of their biosynthesis, but the molecular regulation of that pathway is largely unknown. In an attempt to identify regulators of the biosynthetic flux from acyl-CoA toward phytosterols, we compared the membrane...
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