Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Transcriptional activation of TMSG-1 by complex of KLF6 and Sp1].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Aug 2011

Gong Miao-zi, You Jiang-feng, Pei Fei, Cui Xiang-lin, Li Gang, Zheng Jie

Abstract excerpt

OBJECTIVE: To investigate the regulatory mechanism of the transcription of tumor metastasis suppressor gene TMSG-1. METHODS: Luciferase reporter assay and site-directed mutagenesis were used to analyze the regulatory region of TMSG-1. Electrophoretic mobility shift assay (EMSA) and chromatin immunoprecipitation (ChIP) were carried out to verify the interaction of KLF6 and Sp1 with the regulatory region of TMSG-1....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Electrophoretic Mobility Shift Assay
Share to Immunoprecipitation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kruppel-Like Transcription Factors

Share to Neoplasm Invasiveness

Share to Prostatic Neoplasms

Share to Sp1 Transcription Factor

Share to Transcriptional Activation

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 22169644

Genes

KLF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

[Transcriptional activation of TMSG-1 by complex of KLF6 and Sp1].PMID 22169644Read ↗

Transcription factor SPZ1 promotes TWIST-mediated epithelial–mesenchymal transition and oncogenesis in human liver cancerSemantic proximity Read ↗

[The effects of TMSG-1 gene transfection on metastatic phenotype of pg cancer cells].Semantic proximity Read ↗

Transcriptional activity of Sp1 is regulated by molecular interactions between the zinc finger DNA binding domain and the inhibitory domain with corepressors, and this interaction is modulated by MEK.Semantic proximity Read ↗

Mitogen-activated protein kinase pathway is involved in alpha6 integrin gene expression in androgen-independent prostate cancer cells: role of proximal Sp1 consensus sequence.Semantic proximity Read ↗

IRF1 suppresses Ki-67 promoter activity through interfering with Sp1 activation.Semantic proximity Read ↗

Mitogen-activated protein kinase kinase 4/stress-activated protein/Erk kinase 1 (MKK4/SEK1), a prostate cancer metastasis suppressor gene encoded by human chromosome 17.Semantic proximity Read ↗

TMSG1/LASS2 inhibits cell proliferation, invasive ability through a novel transcriptional regulation way mediated by Homeodomain Running title: a novel transcription regulation role of TMSG1Semantic proximity Read ↗

Transcriptional factor specificity protein 1 (SP1) promotes the proliferation of glioma cells by up-regulating midkine (MDK)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.