Article
The RPT2 subunit of the 26S proteasome directs complex assembly, histone dynamics, and gametophyte and sporophyte development in Arabidopsis.
The Plant cell - 1 Dec 2011
Lee Kwang-Hee, Minami Atsushi, Marshall Richard S, Book Adam J, Farmer Lisa M, Walker Joseph M, Vierstra Richard D
Abstract excerpt
The regulatory particle (RP) of the 26S proteasome contains a heterohexameric ring of AAA-ATPases (RPT1-6) that unfolds and inserts substrates into the core protease (CP) for degradation. Through genetic analysis of the Arabidopsis thaliana gene pair encoding RPT2, we show that this subunit plays a critical role in 26S proteasome assembly, histone dynamics, and plant development. rpt2a rpt2b double null mutants...
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