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Article

Microarray-based mutation detection of pediatric sporadic nonsyndromic hearing loss in China.

International journal of pediatric otorhinolaryngology - 1 Feb 2012

Qu Chunyan, Sun Xibin, Shi Yang, Gong Angela, Liang Shuang, Zhao Min, Chen Yan, Liang Fenghe

Abstract excerpt

OBJECTIVE: To investigate the molecular etiologic causes of sporadic nonsyndromic hearing loss in Chinese children. METHODS: 179 sporadic nonsyndromic hearing loss children were subjected to microarray-based mutation detection for nine hot spot mutations in four of the most common deafness-related genes, including GJB2, SLC26A4, GJB3, and 12s rRNA. RESULTS: The incidence of positive genetic errors was 43.58% with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22154049
DOI: 10.1016/j.ijporl.2011.11.009

Genes

GJB2
GJB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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