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Article

Targeting the Wolbachia Cell Division Protein FtsZ as a New Approach for Antifilarial Therapy

29 Nov 2011

Abstract excerpt

The use of antibiotics targeting the obligate bacterial endosymbiont Wolbachia of filarial parasites has been validated as an approach for controlling filarial infection in animals and humans. Availability of genomic sequences for the Wolbachia (wBm) present in the human filarial parasite Brugia malayi has enabled genome-wide searching for new potential drug targets. In the present study, we investigated the cell...

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PMID: 22140592
DOI: 10.1371/journal.pntd.0001411

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Related research

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Targeting the Wolbachia Cell Division Protein FtsZ as a New Approach for Antifilarial TherapyPMID 22140592Read ↗

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Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodesSemantic proximity Read ↗

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The Heme Biosynthetic Pathway of the Obligate Wolbachia Endosymbiont of Brugia malayi as a Potential Anti-filarial Drug TargetSemantic proximity Read ↗

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