Article
Toll receptors type-2 and CR3 expression of canine monocytes and its correlation with immunohistochemistry and xenodiagnosis in visceral leishmaniasis.
PloS one - 1 Jan 2011
Amorim Izabela Ferreira Gontijo de, Silva Sydnei Magno da, Figueiredo Maria Marta, Moura Eliane Perlatto, Castro Rodrigo Soares de, Lima Tatjana Keesen de Souza, Gontijo Nelder de Figueiredo, Michalick Marilene Suzan Marques, Gollob Kenneth John, Tafuri Wagner Luiz
Abstract excerpt
The aim of the present study was to investigate TLR2 expression in peripheral blood monocytes from dogs naturally infected with Leishmania (Leishmania) infantum to determine whether it correlates with CD11b/CD18 (CR3) expression, and to evaluate the potential of dogs as sources of infection using phlebotomine xenodiagnosis. Forty eight dogs were serologically diagnosed with L. infantum infection by indirect...
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