Article
Rapid detection of blaIMP-6 by amplification refractory mutation system.
Journal of microbiological methods - 1 Jan 2012
Kayama Shizuo, Shigemoto Norifumi, Kuwahara Ryuichi, Onodera Makoto, Yokozaki Michiya, Ohge Hiroki, Kato Fuminori, Hisatsune Jyunzo, Sugai Motoyuki
Abstract excerpt
Klebsiella pneumoniae resistant to almost all ß-lactams except imipenem designated as ISMRK (imipenem-susceptible meropenem-resistant Klebsiella) is emerging in Japan. All ISMRK carries bla(IMP-6) which differs from bla(IMP-1) by only a single nucleotide at position 640. We devised a rapid detection system of bla(IMP-6) by using ARMS PCR.
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