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Article

[Mutation of thyroid peroxidase gene in 35 patients with congenital hypothyroidism].

Zhonghua er ke za zhi = Chinese journal of pediatrics - 1 Aug 2011

Li Hai-fei, Liu Yi-xin, Xie Jian-sheng, Chen Bin, Li Su-li

Abstract excerpt

OBJECTIVE: To identify thyroid peroxidase (TPO) gene mutations in 35 patients with congenital hypothyroidism. METHOD: Genomic DNA was isolated from peripheral blood samples of 35 patients with congenital hypothyroidism. All of the 17 exons and flanking introns of TPO gene were amplified by PCR, then the PCR products were sequenced bi-directionally and were analyzed by restriction endonucleases. RESULT: One...

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Source

Identifiers

PMID: 22093430

Genes

TPO

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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