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Article

Quantitative proteomics reveal up-regulated protein expression of the SET complex associated with hepatocellular carcinoma.

Journal of proteome research - 3 Feb 2012

Li Chen, Ruan Hong-Qiang, Liu Yan-Sheng, Xu Meng-Jie, Dai Jie, Sheng Quan-Hu, Tan Ye-Xiong, Yao Zhen-Zhen, Wang Hong-Yang, Wu Jia-Rui, Zeng Rong

Abstract excerpt

We combined culture-derived isotope tags (CDITs) with two-dimensional liquid chromatography-tandem mass spectrometry (2D-LC-MS/MS) to extensively survey abnormal protein expression associated with hepatocellular carcinoma (HCC) in clinical tissues. This approach yielded an in-depth quantitated proteome of 1360 proteins. Importantly, 267 proteins were significantly regulated with a fold-change of at least 1.5. The...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22082227
DOI: 10.1021/pr2006999

Genes

SET
APEX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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