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Article

Germline genetic testing to predict drug response and toxicity in oncology--reality or fiction?

Annals of the Academy of Medicine, Singapore - 1 Aug 2011

Soh Thomas I P, Yong Wei Peng

Abstract excerpt

In addition to 6-mercaptopurine, 5-fluorouracil and irinotecan, the United States Food and Drug Administration (US FDA) has recently recommended label change for tamoxifen, to include pharmacogenetic information on treatment outcome. With the increasing availability of pharmacogenetic testing, on germline as well as somatic mutations, oncologists are now able to identify individuals at risk of severe treatment...

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PMID: 22065000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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