Article
[Mutations of mitochondrial DNA and their relation to neuromuscular diseases].
Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie - 1 Jan 1990
Wunderlich V
Abstract excerpt
According to present knowledge, mutations of mitochondrial DNA (mtDNA), implicated in the mitochondrial theory of carcinogenesis that had been inaugurated 50 years ago by Graffi, appear to be involved in malignant transformation of cells, although no definite evidence has been provided, as yet. However, as very recently elucidated, a clear-cut association exists between different classes of mutations of mtDNA...
Topics
- DNA, Mitochondrial
- Humans
- Mutation
- Neuromuscular Diseases