Article
In situ hybridization signal patterns in recurrent laryngeal squamous papillomas indicate that HPV integration occurs at an early stage.
Head and neck pathology - 1 Mar 2012
Brooks Erin Grace, Evans Mark Francis, Adamson Christine Stewart-Crawford, Peng Zhihua, Rajendran Vanitha, Laucirica Rodolfo, Cooper Kumarasen
Abstract excerpt
Laryngeal papillomas are benign tumors that frequently recur and can compromise airways. We investigated HPV genotype, physical status, and protein expression in juveniles versus adults. Thirty-five laryngeal papilloma specimens were obtained from ten juveniles (1-16 years) and eleven adults (24-67 years). In cases of recurrent papillomatosis (7 juveniles, 7 adults), the first and last papillomas were assayed....
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