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Article

Significance of Lutein in Red Blood Cells of Alzheimer's Disease Patients

7 Feb 2012

Abstract excerpt

Red blood cells (RBC) of Alzheimer's disease (AD) patients are known to be in an excessively oxidized state (i.e., with a high accumulation of peroxidized phospholipids (PLOOH)). Previously we confirmed in vitro, in vivo murine, and in human studies that carotenoids can effectively inhibit accumulation of RBC PLOOH. Thus, the relationship between RBC carotenoids and PLOOH concentrations in AD patients is of...

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PMID: 22045492
DOI: 10.3233/jad-2011-111493

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