Article
Chemical phenotypes of P2X2 purinoreceptor immunoreactive cell bodies in the area postrema.
Purinergic signalling - 1 Jun 2012
Mangano Chiara, Colldén Gustav, Meister Björn
Abstract excerpt
Purines such as adenosine 5'-triphosphate (ATP) act as extracellular messengers through specific purinergic receptors. Three different classes of purinergic receptors have been identified and termed P1, P2X, and P2Y. The purinergic receptor subunit P2X2 is a ligand-gated ion channel that is widely expressed by neurons in the CNS. In the brainstem medulla oblongata, the ionotropic P2X2 receptor (P2X2R) is enriched...
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