Article
Pegylated interferon-α monotherapy leads to low response rates in HIV-infected patients with acute hepatitis C.
Antiviral therapy - 1 Jan 2011
Arends Joop E, van Assen Sander, Stek Cari J, Wensing Annemarie Mj, Fransen Justin H, Schellens Ingrid M, Spijkers Sanne Nm, Mudrikova Tania, van Baarle Debbie, Sprenger Herman G, Hoepelman Andy Im
Abstract excerpt
BACKGROUND: Despite a rising incidence of acute HCV in patients infected with HIV, the optimal therapeutic strategy (pegylated interferon-α [PEG-IFN-α] monotherapy or in combination with ribavirin) is still under debate. METHODS: A total of 23 HIV-infected patients were prospectively diagnosed with acute HCV and treated with PEG-IFN-α2a monotherapy (180 μg/week) for 24 or 48 weeks. Add-on ribavirin was allowed...
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