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Article

PKP2 mutations in sudden death from arrhythmogenic right ventricular cardiomyopathy (ARVC) and sudden unexpected death with negative autopsy (SUDNA).

Circulation journal : official journal of the Japanese Circulation Society - 1 Jan 2012

Zhang Mingchang, Tavora Fabio, Oliveira Joao Bosco, Li Ling, Franco Marcello, Fowler David, Zhao Ziqin, Burke Allen

Abstract excerpt

BACKGROUND: Plakophilin2 (PKP2) is a desmosome-related protein with numerous armadillo repeats and has been linked to arrhythmogenic right ventricular cardiomyopathy (ARVC). Fatal arrhythmias resulting in sudden death also occur in the absence of morphologic cardiac abnormalities at autopsy, and...

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Source

Identifiers

PMID: 22019812
DOI: 10.1253/circj.cj-11-0747

Genes

PKP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22019812-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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