Article
Neuropathology in classical and variant ataxia-telangiectasia.
Neuropathology : official journal of the Japanese Society of Neuropathology - 1 Jun 2012
Verhagen Mijke M M, Martin Jean-Jacques, van Deuren Marcel, Ceuterick-de Groote Chantal, Weemaes Corry M R, Kremer Berry H P H, Taylor Malcolm A R, Willemsen Michèl A A P, Lammens Martin
Abstract excerpt
Ataxia-telangiectasia (A-T) is classically characterized by progressive neurodegeneration, oculocutaneous telangiectasia, immunodeficiency and elevated α-fetoprotein levels. Some patients, classified as variant A-T, exhibit a milder clinical course. In the latter patients extrapyramidal symptoms, instead of cerebellar ataxia, tend to be the dominating feature and other classical disease hallmarks, like...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.