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Article

The Pcdp1 complex coordinates the activity of dynein isoforms to produce wild-type ciliary motility.

Molecular biology of the cell - 1 Dec 2011

DiPetrillo Christen G, Smith Elizabeth F

Abstract excerpt

Generating the complex waveforms characteristic of beating cilia requires the coordinated activity of multiple dynein isoforms anchored to the axoneme. We previously identified a complex associated with the C1d projection of the central apparatus that includes primary ciliary dyskinesia protein 1 (Pcdp1). Reduced expression of complex members results in severe motility defects, indicating that C1d is essential...

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Identifiers

PMID: 21998195
DOI: 10.1091/mbc.E11-08-0739
PMCID: PMC3226472

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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