Article
Efficacy of genetically modified Bt toxins against insects with different genetic mechanisms of resistance.
Nature biotechnology - 9 Oct 2011
Tabashnik Bruce E, Huang Fangneng, Ghimire Mukti N, Leonard B Rogers, Siegfried Blair D, Rangasamy Murugesan, Yang Yajun, Wu Yidong, Gahan Linda J, Heckel David G, Bravo Alejandra, Soberón Mario
Abstract excerpt
Transgenic crops that produce Bacillus thuringiensis (Bt) toxins are grown widely for pest control, but insect adaptation can reduce their efficacy. The genetically modified Bt toxins Cry1AbMod and Cry1AcMod were designed to counter insect resistance to native Bt toxins Cry1Ab and Cry1Ac. Previous results suggested that the modified toxins would be effective only if resistance was linked with mutations in genes...
Topics
- Animals
- Bacillus thuringiensis
- Bacillus thuringiensis Toxins
- Bacterial Proteins
- Cadherins
- Endotoxins
- Hemolysin Proteins
- Insecta
- Insecticide Resistance
- Moths
- Mutation
- Pest Control, Biological
- Plants, Genetically Modified