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Article

Interspecific Y chromosome introgressions disrupt testis-specific gene expression and male reproductive phenotypes in Drosophila.

Proceedings of the National Academy of Sciences of the United States of America - 11 Oct 2011

Sackton Timothy B, Montenegro Horacio, Hartl Daniel L, Lemos Bernardo

Abstract excerpt

The Drosophila Y chromosome is a degenerated, heterochromatic chromosome with few functional genes. Nonetheless, natural variation on the Y chromosome in Drosophila melanogaster has substantial trans-acting effects on the regulation of X-linked and autosomal genes. However, the contribution of Y chromosome divergence to gene expression divergence between species is unknown. In this study, we constructed a series...

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Identifiers

PMID: 21969588
DOI: 10.1073/pnas.1114690108
PMCID: PMC3193250

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