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Article

Exclusion of CTSB and FDFT1 as positional and functional candidate genes for keratolytic winter erythema (KWE).

Journal of dermatological science - 1 Jan 2012

Hobbs Angela, Aron Shaun, Hartshorne Sian, Hull Peter R, Ramsay Michèle

Abstract excerpt

BACKGROUND: Keratolytic winter erythema (KWE) or Oudtshoorn skin disease is a rare autosomal dominant monogenic disorder of epidermal keratinisation characterized clinically by cyclical peeling of the palms and soles. Due to a founder effect many KWE families have been identified in South Africa and the gene has been localized to 8p23.1-22, but the causal gene has yet to be identified. OBJECTIVE: To examine two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21945151
DOI: 10.1016/j.jdermsci.2011.08.008

Genes

FDFT1
CTSB

Provenance

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Related research

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