Article
Siblings with ischemic stroke study: results of a genome-wide scan for stroke loci.
Stroke - 1 Oct 2011
Meschia James F, Nalls Michael, Matarin Mar, Brott Thomas G, Brown Robert D, Hardy John, Kissela Brett, Rich Stephen S, Singleton Andrew, Hernandez Dena, Ferrucci Luigi, Pearce Kerra, Keller Margaret, Worrall Bradford B
Abstract excerpt
BACKGROUND AND PURPOSE: Ischemic stroke has a strong familial component to risk. The Siblings With Ischemic Stroke Study (SWISS) is a genome-wide, family-based analysis that included use of imputed genotypes. The Siblings With Ischemic Stroke Study was conducted to examine the associations between single-nucleotide polymorphisms (SNPs) and risk of stroke and stroke subtypes within pairs. METHODS: The Siblings...
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