Article
Associations of serotonergic genes with poststroke emotional incontinence.
International journal of geriatric psychiatry - 1 Aug 2012
Kim Jae-Min, Stewart Robert, Kang Hee-Ju, Bae Kyung-Yeol, Kim Sung-Wan, Shin Il-Seon, Kim Joon-Tae, Park Man-Seok, Cho Ki-Hyun, Yoon Jin-Sang
Abstract excerpt
OBJECTIVES: Poststroke emotional incontinence (PSEI) has been associated with serotonergic dysfunction. Polymorphisms of serotonin transporter (5-HTT) and serotonin 2a receptor (5-HTR2a) genes may regulate serotonergic signaling at brain synapses, and this study was to investigate associations with PSEI in an East Asian population. METHODS: In 276 stroke cases, PSEI was diagnosed by Kim's criteria. Covariates...
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