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Article

Mucins in inflammatory bowel diseases and colorectal cancer.

Journal of gastroenterology and hepatology - 1 Jan 2012

Sheng Yong H, Hasnain Sumaira Z, Florin Timothy H J, McGuckin Michael A

Abstract excerpt

The gastrointestinal tract is protected by a mucus barrier with both secreted and cell-surface mucins contributing to the exclusion of luminal microbes and toxins. Alterations in the structure and/or quantity of mucins alter the barrier function of mucus and could play roles in initiating and maintaining mucosal inflammation in inflammatory bowel diseases (IBD), and in driving cancer development in the intestine....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21913981
DOI: 10.1111/j.1440-1746.2011.06909.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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