Article
Wide-range protection against avian reovirus conferred by vaccination with representatives of four defined genotypes.
Vaccine - 3 Nov 2011
Lublin Avishai, Goldenberg Dana, Rosenbluth Ezra, Heller E Dan, Pitcovski Jacob
Abstract excerpt
Many isolates of the contagious avian reovirus have been characterized, mainly based on the sequence of their sigma C protein. These isolates have been classified into four genotypes. Currently available vaccines are of limited effectiveness, likely due to the existence of many variants. The aim of this study was to test the efficacy of a vaccine consisting of a mixture of prototypes (representatives) of the four...
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