Article
Genetic and antigenic characterization of sigma C protein from avian reovirus.
Avian pathology : journal of the W.V.P.A - 1 Jun 2010
Goldenberg Dana, Pasmanik-Chor Metsada, Pirak Michael, Kass Nava, Lublin Avishai, Yeheskel Adva, Heller Dan, Pitcovski Jacob
Abstract excerpt
Avian reovirus (ARV) causes viral arthritis, tenosynovitis, liver infection and immunosuppression in birds. Live-attenuated and inactivated vaccines for ARV are available, but do not efficiently protect against recent variants. Sigma C, which mediates virus attachment to target cells, is the most variable protein in ARV. Antibodies to this protein neutralize viral infection. The purpose of the present study was...
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