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Polar body array CGH for prediction of the status of the corresponding oocyte. Part I: clinical results

9 Sept 2011

Abstract excerpt

BACKGROUND: Several randomized controlled trials have not shown a benefit from preimplantation genetic screening (PGS) biopsy of cleavage-stage embryos and assessment of up to 10 chromosomes for aneuploidy. Therefore, a proof-of-principle study was planned to determine the reliability of alternative form of PGS, i.e. PGS by polar body (PB) biopsy, with whole genome amplification and microarray-based comparative...

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Share to Genomic variations and chromosomal abnormalities
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PMID: 21908463
DOI: 10.1093/humrep/der294

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