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Quantitative and qualitative analyses of the SNRPN gene using real-time PCR with melting curve analysis.

The Journal of molecular diagnostics : JMD - 1 Nov 2011

Hung Chia-Cheng, Lin Shin-Yu, Lin Shuan-Pei, Chen Chih-Ping, Chen Lang-Yao, Lee Chien-Nan, Su Yi-Ning

Abstract excerpt

Prader-Willi syndrome and Angelman syndrome are distinct neurodevelopmental disorders that are associated with the deletion of the chromosomal 15q11-13 region or uniparental disomy of chromosome 15. In this article, we applied SYBR Green I-based real-time PCR and melting curve analysis assay for rapid genotyping of the small nuclear ribonucleoprotein polypeptide N (SNRPN) gene methylation status and for detecting...

Topics

Angelman Syndrome
Benzothiazoles
Chromosomes, Human, Pair 15
DNA Copy Number Variations
DNA Methylation
Diamines
Genotype
Humans
Organic Chemicals
Prader-Willi Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Quinolines

Real-Time Polymerase Chain Reaction

snRNP Core Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 21889609
DOI: 10.1016/j.jmoldx.2011.06.005
PMCID: PMC3194052

Genes

SNRPN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Quantitative and qualitative analyses of the SNRPN gene using real-time PCR with melting curve analysis.PMID 21889609Read ↗

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