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Article

Quantitative and qualitative analyses of the SNRPN gene using real-time PCR with melting curve analysis.

The Journal of molecular diagnostics : JMD - 1 Nov 2011

Hung Chia-Cheng, Lin Shin-Yu, Lin Shuan-Pei, Chen Chih-Ping, Chen Lang-Yao, Lee Chien-Nan, Su Yi-Ning

Abstract excerpt

Prader-Willi syndrome and Angelman syndrome are distinct neurodevelopmental disorders that are associated with the deletion of the chromosomal 15q11-13 region or uniparental disomy of chromosome 15. In this article, we applied SYBR Green I-based real-time PCR and melting curve analysis assay for rapid genotyping of the small nuclear ribonucleoprotein polypeptide N (SNRPN) gene methylation status and for detecting...

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Source

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Identifiers

PMID: 21889609
DOI: 10.1016/j.jmoldx.2011.06.005
PMCID: PMC3194052

Genes

SNRPN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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