Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Silencing of microRNA‐21 in vivo ameliorates autoimmune splenomegaly in lupus mice

1 Sept 2011

Abstract excerpt

MicroRNAs (miRNAs) have been implicated in B cell lineage commitment, regulation of T cell differentiation, TCR signalling, regulation of IFN signalling, and numerous other immunological processes. However, their function in autoimmunity, and specifically in systemic lupus erythematosus (SLE), remains poorly understood. B6.Sle123 is a spontaneous genetic mouse model of SLE characterized by autoantibody...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Cell Function and Interaction
Share to MicroRNA in disease regulation
Share to Systemic Lupus Erythematosus Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21882343
DOI: 10.1002/emmm.201100171

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Silencing of microRNA‐21 in vivo ameliorates autoimmune splenomegaly in lupus micePMID 21882343Read ↗

Immunological Involvement of MicroRNAs in the Key Events of Systemic Lupus ErythematosusSemantic proximity Read ↗

MicroRNA involvement in lupusSemantic proximity Read ↗

MicroRNA-21 deficiency protects from lupus-like autoimmunity in the chronic graft-versus-host disease model of systemic lupus erythematosusSemantic proximity Read ↗

MicroRNA Regulation in Systemic Lupus Erythematosus PathogenesisSemantic proximity Read ↗

Inhibition of miR-22-3p reduces kidney disease associated with systemic lupus erythematosusSemantic proximity Read ↗

Identification of a Common Lupus Disease-Associated microRNA Expression Pattern in Three Different Murine Models of LupusSemantic proximity Read ↗

Regulation of B-cell function by miRNAs impacting Systemic lupus erythematosus progressionSemantic proximity Read ↗

The Involvement of MicroRNAs in Modulation of Innate and Adaptive Immunity in Systemic Lupus Erythematosus and Lupus NephritisSemantic proximity Read ↗

MicroRNAs in the pathogenesis of systemic lupus erythematosus.Semantic proximity Read ↗

Agomir miRNA-150-5p alleviates pristane-induced lupus by suppressing myeloid dendritic cells activation and inflammation via TREM-1 axisSemantic proximity Read ↗

Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression.Semantic proximity Read ↗

MicroRNAs in lupusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.