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Article

Iron modifies plasma FGF23 differently in autosomal dominant hypophosphatemic rickets and healthy humans.

The Journal of clinical endocrinology and metabolism - 1 Nov 2011

Imel Erik A, Peacock Munro, Gray Amie K, Padgett Leah R, Hui Siu L, Econs Michael J

Abstract excerpt

CONTEXT: In autosomal dominant hypophosphatemic rickets (ADHR), fibroblast growth factor 23 (FGF23) resists cleavage, causing increased plasma FGF23 levels. The clinical phenotype includes variable onset during childhood or adulthood and waxing/waning of hypophosphatemia. Delayed onset after puberty in females suggests iron status may be important. OBJECTIVE: Studies were performed to test the hypothesis that...

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Identifiers

PMID: 21880793
DOI: 10.1210/jc.2011-1239
PMCID: PMC3205884

Genes

FGF23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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