Article
Genetic diversity of Plasmodium falciparum shows geographical variation.
The American journal of tropical medicine and hygiene - 1 May 1990
Creasey A, Fenton B, Walker A, Thaithong S, Oliveira S, Mutambu S, Walliker D
Abstract excerpt
Sixty Plasmodium falciparum isolates, 20 each from Thailand, Zimbabwe, and Brazil, were characterized for 20 variant genetic markers, including the enzymes glucose phosphate isomerase, adenosine deaminase and peptidase, 11 other proteins detected by 2-dimensional electrophoresis (2D-PAGE), 2 merozoite surface antigens (MSA-1 and MSA-2), one exported antigen (Exp-1), and sensitivity to the drugs chloroquine,...
Topics
- Alleles
- Animals
- Antigens, Protozoan
- Antimalarials
- Brazil
- Enzymes
- Genetic Markers
- Genetic Variation
- Malaria
- Phenotype
- Plasmodium falciparum
- Polymorphism, Genetic
