Article
Asymptomatic macrothrombocytopenia in a young pure-bred beagle dog: a case report.
Toxicologic pathology - 1 Oct 2011
Bodié Karen, Gagne Gerard D, Sramek Mary K, Desmond David J, Abel Stephen J, Fagerland Jane A
Abstract excerpt
During baseline evaluation prior to a preclinical safety study, a 10-month-old male pure-bred Beagle dog was found to have marked thrombocytopenia (6 × 10(3) platelets [PLT]/µL) associated with a mean platelet volume (MPV) of 17.9 fL. Tests for Rickettsia rickettsii, Ehrlichia canis, and Borrelia burgdorferi were negative. Buccal bleeding time was normal. Over 3 months, PLT were 4 to 141 × 10(3) PLT/µL, and MPV...
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