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Article

Genetics, genomics, and cancer risk assessment: State of the Art and Future Directions in the Era of Personalized Medicine.

CA: a cancer journal for clinicians - 1 Jan 2000

Weitzel Jeffrey N, Blazer Kathleen R, MacDonald Deborah J, Culver Julie O, Offit Kenneth

Abstract excerpt

Scientific and technologic advances are revolutionizing our approach to genetic cancer risk assessment, cancer screening and prevention, and targeted therapy, fulfilling the promise of personalized medicine. In this monograph, we review the evolution of scientific discovery in cancer genetics and genomics, and describe current approaches, benefits, and barriers to the translation of this information to the...

Topics

Genetic Predisposition to Disease
Genetic Testing
Genomics
Humans
Neoplasms
Precision Medicine
Risk Assessment

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 21858794
DOI: 10.3322/caac.20128
PMCID: PMC3346864

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