Article
Founder mutation for α-sarcoglycan-LGMD2D in a Magdalen Islands Acadian cluster.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques - 1 Sept 2011
Tétreault M, Srour M, Allyson J, Thiffault I, Loisel L, Robitaille Y, Bouchard J P, Brais B
Abstract excerpt
BACKGROUND: We have recruited a group of four living and reviewed the records of six deceased distantly related French-Canadians of Acadian descent affected by a childhood-onset form of recessive limb-girdle muscular dystrophy (LGMD). All cases originate from the small archipelago of the Magdalen Islands (population: 13,000) isolated in the Gulf of St-Lawrence. METHODS: Based on the likely sharing of the same...
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