Article
[The role of 1691G>A (Leiden) mutation in Factor V gene, 20210G>A in prothrombin gene and 677C>T in MTHFR gene in etiology of early pregnancy loss].
Ginekologia polska - 1 Jun 2011
Slezak Ryszard, Łaczmański Łukasz, Karpiński Paweł, Reszczyńska-Slezak Dorota
Abstract excerpt
OBJECTIVES: The objective of this study was to investigate the prevalence of common hereditary risk factors for thrombophilia (mutations 1691G>A, 20210G>A and 677C>T variant in factor V Leiden (FV), prothrombin (FII) and MTHFR gene, respectively)--in a cohort of women with early pregnancy loss. MATERIAL AND METHODS: Frequency of mutations in FV, FII and MTHFR was assessed by PCR-RFLP or minisequencing in a cohort...
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