Breakthrough bacteraemia due to tigecycline-resistant Escherichia coli with New Delhi metallo- -lactamase (NDM)-1 successfully treated with colistin in a patient with calciphylaxis

Abstract excerpt

Sir, We present the case of a patient with calciphylaxis and co-infection with New Delhi metallo-β-lactamase (NDM)-1-producing Escherichia coli and Klebsiella pneumoniae, both susceptible to tigecycline and colistin. While receiving tigecycline, the patient developed a bacteraemia due to the NDM-1-positive E. coli, now showing tigecycline resistance. The infection was successfully treated with intravenous...

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