Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Somatization in major depression--clinical features and genetic associations.

Acta psychiatrica Scandinavica - 1 Oct 2011

Klengel T, Heck A, Pfister H, Brückl T, Hennings J M, Menke A, Czamara D, Müller-Myhsok B, Ising M

Abstract excerpt

OBJECTIVE: To identify clinical variables and genetic variations within monoaminergic genes known to be implicated in pain perception that are associated with the occurrence of somatization symptoms in patients with major depression. METHOD: Somatization was evaluated using the respective subscale of the Symptom Checklist SCL-90-R. Six monoaminergic genes were identified showing an involvement in pain perception...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antidepressive Agents
Share to Catechol O-Methyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depressive Disorder, Major

Share to Norepinephrine Plasma Membrane Transport Proteins

Share to Psychiatric Status Rating Scales

Share to Receptor, Serotonin, 5-HT2A

Share to Receptors, Dopamine D4

Share to Tryptophan Hydroxylase

Source

Identifiers

PMID: 21838737
DOI: 10.1111/j.1600-0447.2011.01743.x

Genes

COMT
DRD4
TPH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Somatization in major depression--clinical features and genetic associations.PMID 21838737Read ↗

Cognitive-affective neuroscience of somatization disorder and functional somatic syndromes: reconceptualizing the triad of depression-anxiety-somatic symptoms.Semantic proximity Read ↗

Serotonin transporter gene promoter polymorphism and somatoform symptoms.Semantic proximity Read ↗

Serotonin-related gene pathways associated with undifferentiated somatoform disorder.Semantic proximity Read ↗

Somatic symptoms in depressionSemantic proximity Read ↗

Genome-wide by trait interaction analyses with neuroticism reveal chronic pain-associated depression as a distinct genetic subtypeSemantic proximity Read ↗

Symptoms of somatization as a rapid screening tool for mitochondrial dysfunction in depressionSemantic proximity Read ↗

Dysfunction in Serotonergic and Noradrenergic Systems and Somatic Symptoms in Psychiatric DisordersSemantic proximity Read ↗

Biological underpinnings of the commonalities in depression, somatization, and Chronic Fatigue SyndromeSemantic proximity Read ↗

Biological phenotypes underpin the physio-somatic symptoms of somatization, depression, and chronic fatigue syndrome.Semantic proximity Read ↗

Effect of tryptophan hydroxylase gene polymorphism on aggression in major depressive disorder and undifferentiated somatoform disorder.Semantic proximity Read ↗

Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study.Semantic proximity Read ↗

Polymorphisms in the HTR2A and HTR3A Genes Contribute to Pain in TMD MyalgiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.