Article
Allelic loss of susceptibility loci and the occurrence of BRAF and RAS mutations in patients with familial non-medullary thyroid cancer.
Journal of surgical oncology - 1 Jan 2012
Na Kuk Young, Kim Ra Mi, Song Eun-Mi, Lee Ji Hyun, Lee Jandee, Soh Euy-Young
Abstract excerpt
OBJECTIVES: Approximately 5% of non-medullary thyroid cancer (NMTC) diagnoses are made against a background of familial predisposition and, in such instances, the disease is termed familial non-medullary thyroid cancer (FNMTC). To date, neither genetic alterations causing FNMTC nor genes predisposing to the condition have been described. The objective of the present study was to evaluate loss of heterozygosity...
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