Article
Leukocyte composition of human breast cancer.
Proceedings of the National Academy of Sciences of the United States of America - 21 Feb 2012
Ruffell Brian, Au Alfred, Rugo Hope S, Esserman Laura J, Hwang E Shelley, Coussens Lisa M
Abstract excerpt
Retrospective clinical studies have used immune-based biomarkers, alone or in combination, to predict survival outcomes for women with breast cancer (BC); however, the limitations inherent to immunohistochemical analyses prevent comprehensive descriptions of leukocytic infiltrates, as well as evaluation of the functional state of leukocytes in BC stroma. To more fully evaluate this complexity, and to gain insight...
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